Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

Podocin is a key protein of the kidney podocyte slit diaphragm protein complex, an important part of the glomerular filtration barrier. Mutations in the human podocin gene NPHS2 cause familial or sporadic forms of renal disease owing to the disruption of filtration barrier integrity. The exclusive e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: He, Bing, Ebarasi, Lwaki, Zhao, Zhe, Guo, Jing, Ojala, Juha R.M., Hultenby, Kjell, De Val, Sarah, Betsholtz, Christer, Tryggvason, Karl
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2014
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243338/
https://ncbi.nlm.nih.gov/pubmed/24854274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012080823
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