Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes

Podocin is a key protein of the kidney podocyte slit diaphragm protein complex, an important part of the glomerular filtration barrier. Mutations in the human podocin gene NPHS2 cause familial or sporadic forms of renal disease owing to the disruption of filtration barrier integrity. The exclusive e...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: He, Bing, Ebarasi, Lwaki, Zhao, Zhe, Guo, Jing, Ojala, Juha R.M., Hultenby, Kjell, De Val, Sarah, Betsholtz, Christer, Tryggvason, Karl
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2014
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243338/
https://ncbi.nlm.nih.gov/pubmed/24854274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012080823
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