Rhophilin-1 Is a Key Regulator of the Podocyte Cytoskeleton and Is Essential for Glomerular Filtration

Rhophilin-1 is a Rho GTPase-interacting protein, the biologic function of which is largely unknown. Here, we identify and describe the functional role of Rhophilin-1 as a novel podocyte-specific protein of the kidney glomerulus. Rhophilin-1 knockout mice were phenotypically normal at birth but devel...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Lal, Mark A., Andersson, Ann-Charlotte, Katayama, Kan, Xiao, Ziejie, Nukui, Masatoshi, Hultenby, Kjell, Wernerson, Annika, Tryggvason, Karl
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2015
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341472/
https://ncbi.nlm.nih.gov/pubmed/25071083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013111195
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