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Monoclonal antibodies to T-2 toxin. In vitro neutralization of protein synthesis inhibition and protection of rats against lethal toxemia.

A murine monoclonal antibody (15H6) against the trichothecene mycotoxin T-2 was capable of neutralizing the in vitro protein synthesis inhibitory effect of T-2 toxin in human B lymphoblastoid cultures. It was further shown that 15H6 given to rats (250 mg/kg) 30 min before or 15 min after a lethal do...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Feuerstein, G, Powell, J A, Knower, A T, Hunter, K W
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1985
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424326/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4077976/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112218
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