Comparative in vitro and in vivo assessment of toxin neutralization by anti-tetanus toxin monoclonal antibodies

Tetanus is caused by the tetanus neurotoxin (TeNT), a 150 kDa single polypeptide molecule which is cleaved into an active two-chain molecule composed of a 50 kDa N-terminal light (L) and a 100 kDa C-terminal heavy (H) chains. Recently, extensive effort has focused on characterization of TeNT binding...

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מידע ביבליוגרפי
Main Authors: Yousefi, Mehdi, Khosravi-Eghbal, Roya, Reza Mahmoudi, Ahmad, Jeddi-Tehrani, Mahmood, Rabbani, Hodjatallah, Shokri, Fazel
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2014
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185888/
https://ncbi.nlm.nih.gov/pubmed/24126015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26769
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