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Comparative in vitro and in vivo assessment of toxin neutralization by anti-tetanus toxin monoclonal antibodies
Tetanus is caused by the tetanus neurotoxin (TeNT), a 150 kDa single polypeptide molecule which is cleaved into an active two-chain molecule composed of a 50 kDa N-terminal light (L) and a 100 kDa C-terminal heavy (H) chains. Recently, extensive effort has focused on characterization of TeNT binding...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185888/ https://ncbi.nlm.nih.gov/pubmed/24126015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26769 |
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