Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury

Oxidative stress is a common denominator of numerous cardiovascular disorders. Free cellular iron catalyzes formation of highly toxic hydroxyl radicals and iron chelation may thus be an effective therapeutic approach. However, using classical iron chelators in diseases without iron overload poses ri...

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Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Jansová, Hana, Macháček, Miloslav, Wang, Qin, Hašková, Pavlína, Jirkovská, Anna, Potůčková, Eliška, Kielar, Filip, Franz, Katherine J., Šimůnek, Tomáš
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243170/
https://ncbi.nlm.nih.gov/pubmed/24992833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.06.019
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