Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties

Although general anesthetics are clinically important and widely used, their molecular mechanisms of action remain poorly understood. Volatile anesthetics such as isoflurane (ISO) are thought to alter neuronal function by depressing excitatory and facilitating inhibitory neurotransmission through di...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Main Authors: Herold, Karl F., Sanford, R. Lea, Lee, William, Schultz, Margaret F., Ingólfsson, Helgi I., Andersen, Olaf S., Hemmings, Hugh C.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242807/
https://ncbi.nlm.nih.gov/pubmed/25385786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411172
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