Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties

Although general anesthetics are clinically important and widely used, their molecular mechanisms of action remain poorly understood. Volatile anesthetics such as isoflurane (ISO) are thought to alter neuronal function by depressing excitatory and facilitating inhibitory neurotransmission through di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gen Physiol
Prif Awduron: Herold, Karl F., Sanford, R. Lea, Lee, William, Schultz, Margaret F., Ingólfsson, Helgi I., Andersen, Olaf S., Hemmings, Hugh C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2014
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242807/
https://ncbi.nlm.nih.gov/pubmed/25385786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411172
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