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A multiplexed fluorescent assay for independent second messenger systems: Decoding GPCR activation in living cells

There is a growing need in drug discovery and basic research to measure multiple second messenger components of cell signaling pathways in real time and in relevant tissues and cell types. Many G-protein coupled receptors activate the heterotrimeric protein, Gq, which in turn activates phospholipase...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Tewson, Paul, Quinn, Anne Marie, Hughes, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242713/
https://ncbi.nlm.nih.gov/pubmed/23580666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113485427
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