A Multiplexed Fluorescent Calcium and NFAT Reporter Gene Assay to Identify GPCR Agonists

Intracellular calcium response and resulting calcium signaling to an agonist-GPCR interaction are important for the measurement of compound activity in the GPCR drug development. The increase in cytosol calcium concentration can be measured by the fluorescent calcium indicator dye such as Fluo-4 in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sheth, Heeral, Gorey, Colleen, Roush, Nicole, Smallman, Shelly, Collantes, Elizabeth, Santoro, Maxine, Olson, Barbara, Fitzgerald, Laura, Lee, Paul H, Shen, Xiqiang John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Bentham Open 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854663/
https://ncbi.nlm.nih.gov/pubmed/24396729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501307010001
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