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Polycationic calixarene PTX013, a potent cytotoxic agent against tumors and drug resistant cancer
Previously, we reported on the anti-tumor activities of two designed calix[4]arene-based topomimetics (PTX008 and PTX009) of the amphipathic, angiostatic peptide Anginex. Here, we chemically modified the hydrophobic and hydrophilic faces of PTX008 and PTX009, and discovered new calixarene compounds...
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| Publicado no: | Invest New Drugs |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242102/ https://ncbi.nlm.nih.gov/pubmed/23392775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-9932-0 |
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