Structure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1

Galectin-1 (gal-1), which binds β-galactoside groups on various cell surface receptors, is crucial to cell adhesion and migration, and is found to be elevated in several cancers. Previously, we reported on 6DBF7, a dibenzofuran (DBF)-based peptidomimetic of the gal-1 antagonist anginex. In the prese...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dings, Ruud P. M., Kumar, Nigam, Miller, Michelle C., Loren, Melissa, Rangwala, Huzaifa, Hoye, Thomas R., Mayo, Kevin H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2013
Gaiak:
Drug Discovery and Translational Medicine
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583509/
https://ncbi.nlm.nih.gov/pubmed/23232447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199646
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak