Enhancement of T-cell mediated anti-tumor response: angiostatic adjuvant to immunotherapy against cancer

PURPOSE: Tumor-released pro-angiogenic factors suppress endothelial adhesion molecule (EAM) expression and prevent leukocyte extravasation into the tumor. This is one reason why immunotherapy has met with limited success in the clinic. We hypothesized that overcoming EAM suppression with angiogenesi...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Dings, Ruud P.M., Vang, Kieng B., Castermans, Karolien, Popescu, Flavia, Zhang, Yan, oude Egbrink, Mirjam G. A., Mescher, Matthew F., Farrar, Michael A., Griffioen, Arjan W., Mayo, Kevin H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242153/
https://ncbi.nlm.nih.gov/pubmed/21252159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2443
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