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Disparate mechanisms for hypoxic cell injury in different nephron segments. Studies in the isolated perfused rat kidney.

Hypoxic injury was evaluated morphologically in the proximal tubule and in the medullary thick ascending limb of isolated rat kidneys perfused for 90 min without O2 or with various metabolic inhibitors. Inhibition of mitochondrial respiration (with rotenone, antimycin, oligomycin) or of intermediary...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Brezis, M, Shanley, P, Silva, P, Spokes, K, Lear, S, Epstein, F H, Rosen, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424210/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4056054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112171
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