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Disparate mechanisms for hypoxic cell injury in different nephron segments. Studies in the isolated perfused rat kidney.

Hypoxic injury was evaluated morphologically in the proximal tubule and in the medullary thick ascending limb of isolated rat kidneys perfused for 90 min without O2 or with various metabolic inhibitors. Inhibition of mitochondrial respiration (with rotenone, antimycin, oligomycin) or of intermediary...

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Bibliographic Details
Main Authors: Brezis, M, Shanley, P, Silva, P, Spokes, K, Lear, S, Epstein, F H, Rosen, S
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424210/
https://ncbi.nlm.nih.gov/pubmed/4056054
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