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Prevalence and natural history of ALK positive non-small-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors

Improved understanding of molecular drivers of carcinogenesis has led to significant progress in the management of lung cancer. Patients with non-small-cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK) gene rearrangements constitute about 4%–5% of all NSCLC patients. ALK+ NSCLC cells re...

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Dettagli Bibliografici
Pubblicato in:Clin Epidemiol
Autori principali: Chia, Puey Ling, Mitchell, Paul, Dobrovic, Alexander, John, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242069/
https://ncbi.nlm.nih.gov/pubmed/25429239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CLEP.S69718
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