Transcriptomics-Guided Personalized Prescription of Targeted Therapeutics for Metastatic ALK-Positive Lung Cancer Case Following Recurrence on ALK Inhibitors

Non-small cell lung carcinoma (NSCLC) is the major cause of cancer-associated mortality. Identification of rearrangements in anaplastic lymphoma kinase (ALK) gene is an effective instrument for more effective targeted therapy of NSCLC using ALK inhibitors dramatically raising progression-free surviv...

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Udgivet i:Front Oncol
Main Authors: Poddubskaya, Elena, Bondarenko, Alexey, Boroda, Alexander, Zotova, Evgenia, Glusker, Alex, Sletina, Svetlana, Makovskaia, Luidmila, Kopylov, Philipp, Sekacheva, Marina, Moisseev, Alexey, Baranova, Madina
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803543/
https://ncbi.nlm.nih.gov/pubmed/31681574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01026
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