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Prevalence and natural history of ALK positive non-small-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors

Improved understanding of molecular drivers of carcinogenesis has led to significant progress in the management of lung cancer. Patients with non-small-cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK) gene rearrangements constitute about 4%–5% of all NSCLC patients. ALK+ NSCLC cells re...

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Detalhes bibliográficos
Publicado no:Clin Epidemiol
Main Authors: Chia, Puey Ling, Mitchell, Paul, Dobrovic, Alexander, John, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242069/
https://ncbi.nlm.nih.gov/pubmed/25429239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CLEP.S69718
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