Directional Selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan Children Treated With ACT

BACKGROUND: The efficacy of artemisinin-based combination therapy (ACT) for Plasmodium falciparum malaria may be threatened by parasites with reduced responsiveness to artemisinins. Among 298 ACT-treated children from Mbita, Kenya, submicroscopic persistence of P. falciparum on day 3 posttreatment w...

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Publicado en:J Infect Dis
Autores principales: Henriques, Gisela, Hallett, Rachel L., Beshir, Khalid B., Gadalla, Nahla B., Johnson, Rachel E., Burrow, Rebekah, van Schalkwyk, Donelly A., Sawa, Patrick, Omar, Sabah A., Clark, Taane G., Bousema, Teun, Sutherland, Colin J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241946/
https://ncbi.nlm.nih.gov/pubmed/24994911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu358
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