Ixabepilone-induced mitochondria and sensory axon loss in breast cancer patients

BACKGROUND: We sought to define the clinical and ultrastructure effects of ixabepilone (Ix), a microtubule-stabilizing chemotherapy agent on cutaneous sensory nerves and to investigate a potential mitochondrial toxicity mechanism. METHODS: Ten breast cancer patients receiving Ix underwent total neur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Clin Transl Neurol
Egile Nagusiak: Ebenezer, Gigi J, Carlson, Karen, Donovan, Diana, Cobham, Marta, Chuang, Ellen, Moore, Anne, Cigler, Tessa, Ward, Maureen, Lane, Maureen E, Ramnarain, Anita, Vahdat, Linda T, Polydefkis, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2014
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241791/
https://ncbi.nlm.nih.gov/pubmed/25493278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.90
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