Neutron Reflectometry Studies Define Prion Protein N-terminal Peptide Membrane Binding

The prion protein (PrP), widely recognized to misfold into the causative agent of the transmissible spongiform encephalopathies, has previously been shown to bind to lipid membranes with binding influenced by both membrane composition and pH. Aside from the misfolding events associated with prion pa...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Le Brun, Anton P., Haigh, Cathryn L., Drew, Simon C., James, Michael, Boland, Martin P., Collins, Steven J.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2014
Materias:
Membranes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241452/
https://ncbi.nlm.nih.gov/pubmed/25418300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.09.027
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