Neutron Reflectometry Study of the Conformation of HIV Nef Bound to Lipid Membranes

Nef is an HIV-1 accessory protein that directly contributes to AIDS progression. Nef is myristoylated on the N-terminus, associates with membranes, and may undergo a transition from a solution conformation to a membrane-associated conformation. It has been hypothesized that conformational rearrangem...

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Main Authors: Kent, Michael S., Murton, Jaclyn K., Sasaki, Darryl Y., Satija, Sushil, Akgun, Bulent, Nanda, Hirsh, Curtis, Joseph E., Majewski, Jaroslaw, Morgan, Christopher R., Engen, John R.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Protein
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941035/
https://ncbi.nlm.nih.gov/pubmed/20858440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.016
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