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Two Classes of Cholesterol Binding Sites for the β(2)AR Revealed by Thermostability and NMR
Cholesterol binding to G protein-coupled receptors (GPCRs) and modulation of their activities in membranes is a fundamental issue for understanding their function. Despite the identification of cholesterol binding sites in high-resolution x-ray structures of the β(2) adrenergic receptor (β(2)AR) and...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241438/ https://ncbi.nlm.nih.gov/pubmed/25418299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.011 |
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