Yüklüyor......
Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket
[Image: see text] The stress-inducible mammalian heat shock protein 70 (HSP70) and its bacterial orthologue DnaK are highly conserved nucleotide binding molecular chaperones. They represent critical regulators of cellular proteostasis, especially during conditions of enhanced stress. Cancer cells re...
Kaydedildi:
| Yayımlandı: | ACS Chem Biol |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical
Society
2014
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241170/ https://ncbi.nlm.nih.gov/pubmed/25148104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500236y |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|