High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the oxidative phosphorylation of d-glyceraldehyde 3-phosphate (G3P) into 1,3-diphosphoglycerate (BGP) in the presence of the NAD cofactor. GAPDH is an important drug target because of its central role in glycolysis, and nonglycolytic process...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Baker, Bo Y, Shi, Wuxian, Wang, Benlian, Palczewski, Krzysztof
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241113/
https://ncbi.nlm.nih.gov/pubmed/25176140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2543
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