High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the oxidative phosphorylation of d-glyceraldehyde 3-phosphate (G3P) into 1,3-diphosphoglycerate (BGP) in the presence of the NAD cofactor. GAPDH is an important drug target because of its central role in glycolysis, and nonglycolytic process...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Protein Sci
Huvudupphovsmän: Baker, Bo Y, Shi, Wuxian, Wang, Benlian, Palczewski, Krzysztof
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2014
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241113/
https://ncbi.nlm.nih.gov/pubmed/25176140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2543
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk