Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer Disease: Many Pathways to Neurodegeneration

Recently, the oxidoreductase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), has become a subject of interest as more and more studies reveal a surfeit of diverse GAPDH functions, extending beyond traditional aerobic metabolism of glucose. As a result of multiple isoforms and cellular locales, GA...

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Hauptverfasser: Butterfield, D. Allan, Hardas, Sarita S., Bader Lange, Miranda L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922983/
https://ncbi.nlm.nih.gov/pubmed/20164570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1375
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