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Structural and mutational studies on an aldo-keto reductase AKR5C3 from Gluconobacter oxydans

An aldo-keto reductase AKR5C3 from Gluconobacter oxydans (designated as Gox0644) is a useful enzyme with various substrates, including aldehydes, diacetyl, keto esters, and α-ketocarbonyl compounds. The crystal structures of AKR5C3 in apoform in complex with NADPH and the D53A mutant (AKR5C3(-D53A))...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Liu, Xu, Wang, Chao, Zhang, Lujia, Yao, Zhiqiang, Cui, Dongbing, Wu, Liang, Lin, Jinping, Yuan, Yu-Ren Adam, Wei, Dongzhi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241105/
https://ncbi.nlm.nih.gov/pubmed/25131535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2531
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