Inhibitory role of phosphatidylinositol 4,5-bisphosphate on TMEM16A-encoded calcium-activated chloride channels in rat pulmonary artery

BACKGROUND AND PURPOSE: Calcium-activated chloride channels (CaCCs) are key depolarizing mechanisms that have an important role in vascular smooth muscle contraction. Here, we investigated whether these channels are regulated by phosphatidylinositol (4,5) bisphosphate [P(4,5)P(2)], a known regulator...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Pritchard, H A T, Leblanc, N, Albert, A P, Greenwood, I A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241096/
https://ncbi.nlm.nih.gov/pubmed/24834965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12778
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