Defensins. Natural peptide antibiotics of human neutrophils.

We extracted a granule-rich sediment from normal human neutrophils and subjected it to chromatographic, electrophoretic, and functional analysis. The extract contained three small (molecular weight less than 3,500) antibiotic peptides that were named human neutrophil peptide (HNP)-1, HNP-2, and HNP-...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Ganz, T, Selsted, M E, Szklarek, D, Harwig, S S, Daher, K, Bainton, D F, Lehrer, R I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2997278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112120
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