Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin.

A broad-spectrum antimicrobial peptide present in guinea pig neutrophils was isolated, characterized biochemically, and assessed for microbicidal range and potency in vitro. The guinea pig neutrophil peptide (GPNP) was purified to homogeneity from a granule-rich subcellular fraction of peritoneal ex...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Selsted, M E, Harwig, S S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3623703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.9.2281-2286.1987
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