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Mouse neutrophils lack defensins.

Defensins are broad-spectrum antimicrobial peptides that are abundant in human, rat, and rabbit neutrophils. We now report that neutrophils from nine strains of mice lacked appreciable defensin content. Mice may therefore be imperfect experimental surrogates for humans or rats in models of infection...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Eisenhauer, P B, Lehrer, R I
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257335/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639513/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.8.3446-3447.1992
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