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Defensins. Natural peptide antibiotics of human neutrophils.

We extracted a granule-rich sediment from normal human neutrophils and subjected it to chromatographic, electrophoretic, and functional analysis. The extract contained three small (molecular weight less than 3,500) antibiotic peptides that were named human neutrophil peptide (HNP)-1, HNP-2, and HNP-...

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Bibliographic Details
Main Authors: Ganz, T, Selsted, M E, Szklarek, D, Harwig, S S, Daher, K, Bainton, D F, Lehrer, R I
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424093/
https://ncbi.nlm.nih.gov/pubmed/2997278
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