Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity

BACKGROUND: Although genome-wide association studies (GWAS) have identified hundreds of variants associated with a risk for autoimmune and immune-related disorders (AID), our understanding of the disease mechanisms is still limited. In particular, more than 90% of the risk variants lie in non-coding...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Genome Med
Autori principali: Hrdlickova, Barbara, Kumar, Vinod, Kanduri, Kartiek, Zhernakova, Daria V, Tripathi, Subhash, Karjalainen, Juha, Lund, Riikka J, Li, Yang, Ullah, Ubaid, Modderman, Rutger, Abdulahad, Wayel, Lähdesmäki, Harri, Franke, Lude, Lahesmaa, Riitta, Wijmenga, Cisca, Withoff, Sebo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240855/
https://ncbi.nlm.nih.gov/pubmed/25419237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0088-0
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