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Ischemic Preconditioning Inhibits Mitochondrial Permeability Transitional Pore Opening through the PTEN/PDE4 Signaling Pathway
OBJECTIVES: Ischemic preconditioning (IPC) induces cardioprotection against ischemia-reperfusion (IR) injury by inhibiting the mitochondrial permeability transition pore (mPTP). Here, we tested the hypothesis that IPC-induced cardioprotection is mediated by the phosphatase PTEN and phosphodiesterase...
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| Опубликовано в: : | Cardiology |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4240802/ https://ncbi.nlm.nih.gov/pubmed/25301476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363646 |
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