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Ischemic Preconditioning Inhibits Mitochondrial Permeability Transitional Pore Opening through the PTEN/PDE4 Signaling Pathway
OBJECTIVES: Ischemic preconditioning (IPC) induces cardioprotection against ischemia-reperfusion (IR) injury by inhibiting the mitochondrial permeability transition pore (mPTP). Here, we tested the hypothesis that IPC-induced cardioprotection is mediated by the phosphatase PTEN and phosphodiesterase...
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Publicado no: | Cardiology |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4240802/ https://ncbi.nlm.nih.gov/pubmed/25301476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363646 |
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