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Pharmacokinetics of a controlled-release liposome-encapsulated hydromorphone administered to healthy dogs

The purpose of the study was to assess the pharmacokinetics of liposome-encapsulated (DPPC-C) hydromorphone administered intravenously (IV) or subcutaneously (SC) to dogs. A total of eight healthy Beagles aged 12.13 ± 1.2 months and weighing 11.72 ± 1.10 kg were used. Dogs randomly received liposome...

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Publicado en:J Vet Pharmacol Ther
Main Authors: SMITH, L. J., KuKANICH, B., HOGAN, B. K., BROWN, C., HEATH, T. D., KRUGNER-HIGBY, L. A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240744/
https://ncbi.nlm.nih.gov/pubmed/19000260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2885.2008.00974.x
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