Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation.

The mechanism of neutrophil activation by the chemotactic peptide formyl-methionyl-leucyl-phenylalanine (FMLP) has been studied by pretreatment of human neutrophils with pertussis toxin. Upon stimulation with FMLP, the cytosolic-free calcium concentration, [Ca2+]i, is increased both by stimulation o...

Full description

Saved in:
Bibliographic Details
Main Authors: Krause, K H, Schlegel, W, Wollheim, C B, Andersson, T, Waldvogel, F A, Lew, P D
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424072/
https://ncbi.nlm.nih.gov/pubmed/3877077
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items