A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor.

The chemotactic peptide N-formyl-Nle-Leu-Phe-Nle-Tyr(125I)-Lys (formyl 125I-peptide) binds in a saturable manner to human promyelocytic leukemia cells (HL-60) grown in suspension culture. The binding is of high affinity (50% binding at 0.4--0.75 nM), is rapid (half-time at 22 degrees C = 10 min), is...

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Bibliographic Details
Main Authors: Niedel, J, Kahane, I, Lachman, L, Cuatrecasas, P
Format: Artigo
Language:Inglês
Published: 1980
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC348411/
https://ncbi.nlm.nih.gov/pubmed/6928654
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