Role of Focal Adhesion Tyrosine Kinases in GPVI-Dependent Platelet Activation and Reactive Oxygen Species Formation

BACKGROUND: We have previously shown the presence of a TRAF4/p47(phox)/Hic5/Pyk2 complex associated with the platelet collagen receptor, GPVI, consistent with a potential role of this complex in GPVI-dependent ROS formation. In other cell systems, NOX-dependent ROS formation is facilitated by Pyk2,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carrim, Naadiya, Walsh, Tony G., Consonni, Alessandra, Torti, Mauro, Berndt, Michael C., Metharom, Pat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240642/
https://ncbi.nlm.nih.gov/pubmed/25415317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113679
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