Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes.

Freshly isolated human neutrophils were investigated for their ability to degrade heparan sulfate proteoglycans in the subendothelial extracellular matrix (ECM) produced by cultured corneal and vascular endothelial cells. The ECM was metabolically labeled with Na2(35S)O4 and labeled degradation prod...

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Argitaratua izan da:	J Clin Invest
Egile Nagusiak:	Matzner, Y, Bar-Ner, M, Yahalom, J, Ishai-Michaeli, R, Fuks, Z, Vlodavsky, I
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Clinical Investigation 1985
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2997275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112104
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