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Cyclin B1 Overexpression Induces Cell Death Independent of Mitotic Arrest

Microtubule inhibitors are widely used in cancer chemotherapy. These drugs characteristically induce mitotic arrest and cell death but the mechanisms linking the two are not firmly established. One of the problems is that cancer cells vary widely in their sensitivity to these agents, and thus compar...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Eichhorn, Joshua M., Kothari, Anisha, Chambers, Timothy C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240608/
https://ncbi.nlm.nih.gov/pubmed/25415322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113283
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