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Cyclin B1 Overexpression Induces Cell Death Independent of Mitotic Arrest

Microtubule inhibitors are widely used in cancer chemotherapy. These drugs characteristically induce mitotic arrest and cell death but the mechanisms linking the two are not firmly established. One of the problems is that cancer cells vary widely in their sensitivity to these agents, and thus compar...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Eichhorn, Joshua M., Kothari, Anisha, Chambers, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240608/
https://ncbi.nlm.nih.gov/pubmed/25415322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113283
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