Cholesterol, Oxysterol, Triglyceride, and Coenzyme Q Homeostasis in ALS. Evidence against the Hypothesis That Elevated 27-Hydroxycholesterol Is a Pathogenic Factor

High plasma levels of cholesterol have been suggested to be neuroprotective for the degenerative disease amyotrophic lateral sclerosis (ALS) and to be associated with increased survival time. The gene encoding cholesterol 27-hydroxylase, CYP27A1, was recently identified as a susceptibility gene for...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Wuolikainen, Anna, Acimovic, Jure, Lövgren-Sandblom, Anita, Parini, Paolo, Andersen, Peter M., Björkhem, Ingemar
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240598/
https://ncbi.nlm.nih.gov/pubmed/25415378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113619
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