Cholesterol, Oxysterol, Triglyceride, and Coenzyme Q Homeostasis in ALS. Evidence against the Hypothesis That Elevated 27-Hydroxycholesterol Is a Pathogenic Factor

High plasma levels of cholesterol have been suggested to be neuroprotective for the degenerative disease amyotrophic lateral sclerosis (ALS) and to be associated with increased survival time. The gene encoding cholesterol 27-hydroxylase, CYP27A1, was recently identified as a susceptibility gene for...

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Pubblicato in:PLoS One
Autori principali: Wuolikainen, Anna, Acimovic, Jure, Lövgren-Sandblom, Anita, Parini, Paolo, Andersen, Peter M., Björkhem, Ingemar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240598/
https://ncbi.nlm.nih.gov/pubmed/25415378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113619
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