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SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation

While the majority of cancer patients are exposed to ionizing radiation during diagnostic and therapeutic procedures, age-dependent differences in radiation sensitivity are not yet well understood. Radiation sensitivity is characterized by the appearance of side effects to radiation therapy, such as...

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Podrobná bibliografie
Vydáno v:Front Genet
Hlavní autoři: Sidler, Corinne, Li, Dongping, Wang, Bo, Kovalchuk, Igor, Kovalchuk, Olga
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240170/
https://ncbi.nlm.nih.gov/pubmed/25484892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00411
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