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A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts

Cellular senescence has been associated with the age-dependent decline in tissue repair and regeneration, the increasing deterioration of the immune system, and the age-dependent increase in the incidence of cancer. Here, we show that senescence of human lung fibroblast WI-38 cells is associated wit...

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Autors principals: Sidler, Corinne, Woycicki, Rafal, Li, Dongping, Wang, Bo, Kovalchuk, Igor, Kovalchuk, Olga
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153622/
https://ncbi.nlm.nih.gov/pubmed/25063769
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