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SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation

While the majority of cancer patients are exposed to ionizing radiation during diagnostic and therapeutic procedures, age-dependent differences in radiation sensitivity are not yet well understood. Radiation sensitivity is characterized by the appearance of side effects to radiation therapy, such as...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Sidler, Corinne, Li, Dongping, Wang, Bo, Kovalchuk, Igor, Kovalchuk, Olga
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240170/
https://ncbi.nlm.nih.gov/pubmed/25484892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00411
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