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SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation

While the majority of cancer patients are exposed to ionizing radiation during diagnostic and therapeutic procedures, age-dependent differences in radiation sensitivity are not yet well understood. Radiation sensitivity is characterized by the appearance of side effects to radiation therapy, such as...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Sidler, Corinne, Li, Dongping, Wang, Bo, Kovalchuk, Igor, Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240170/
https://ncbi.nlm.nih.gov/pubmed/25484892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00411
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