Evaluation of effect of impaired renal function on lamivudine pharmacokinetics

AIMS: This study aimed to describe lamivudine pharmacokinetics in patients with impaired renal function and to evaluate the consistency of current dosing recommendations. METHODS: A total of 244 patients, ranging in age from 18 to 79 years (median 40 years) and in bodyweight from 38 to 117 kg (media...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Bouazza, Naïm, Tréluyer, Jean-Marc, Ghosn, Jade, Hirt, Déborah, Benaboud, Sihem, Foissac, Frantz, Viard, Jean-Paul, Urien, Saik
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239978/
https://ncbi.nlm.nih.gov/pubmed/24750102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12407
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