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Cyclo-oxygenase-2 inhibition and endothelium-dependent vasodilation in younger vs. older healthy adults

AIM: A major feature of endothelial dysfunction is reduced endothelium-dependent vasodilation, which in ageing may be due to decreased production of endothelial prostacyclin, or nitric oxide (NO), or both. METHOD: We tested this hypothesis in 12 younger (age 18–38 years, six women) and 12 older heal...

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Podrobná bibliografie
Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Eisenach, John H, Gullixson, Leah R, Allen, Alexander R, Kost, Susan L, Nicholson, Wayne T
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239975/
https://ncbi.nlm.nih.gov/pubmed/24698105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12397
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